Presence of Kaposi's Sarcoma and of Behcet’s Disease Concomitantly in a Patient

  • Murthy MS
  • Cody Lawrence
  • Todd Brown
  • Shanika Sharma
Keywords: Behcet Disease, Iatrogenic Kaposi Sarcoma, Immunosuppressive Therapy

Abstract

Iatrogenic Kaposi’s sarcoma is a subtype of Kaposi’s sarcoma (KS), which is a vascular malignant tumor and is seen in organ transplant recipients and in patients receiving immunosuppressive therapy due to other reasons. We describe a case of Behcet's disease associated with Kaposi's sarcoma occurring simultaneously in a 50-year-old male patient. Colchicine and steroids were administered for his mucocutaneous findings and polyarthritis. In few months on therapy, four symmetric, brown- red coloured, asymptomatic macules developed on the inner surface of his left foot. In histopathologic specimens; CD34 positive, atypical spindle cells with swollen nuclei formed bundles and vascular spaces filled with erythrocytes. The patient was diagnosed as KS clinically and histopathologically. HHV-8 DNA was positive with PCR. Regression was observed in the lesions after the cessation of corticosteroid treatment.

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Author Biographies

Murthy MS

MD (Internal Medicine), Private Practitioner, Roy, Utah, United States of America.

Cody Lawrence

MD (Internal Medicine), Private Practitioner, Roy, Utah, United States of America.

Todd Brown

MBBS, Private Practitioner, Pokhara, Nepal, India.

Shanika Sharma

MBBS, Private Practitioner, Pokhara, Nepal, India.

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CITATION
DOI: 10.26440/IHRJ/0611.02591
Published: 2023-03-12
How to Cite
1.
Murthy MS, Cody Lawrence, Todd Brown, Shanika Sharma. Presence of Kaposi’s Sarcoma and of Behcet’s Disease Concomitantly in a Patient. IHRJ [Internet]. 2023Mar.12 [cited 2024Mar.2];6(12):RV1-RV3. Available from: https://ihrjournal.com/ihrj/article/view/591