Oral cancer is a common disease which affects individuals of mainly the older age group. If diagnosed at later stages, the prognosis is poor. In this review, the various techniques for diagnosis of oral cancer such as screening of the patient by conventional oral examination, supravital staining, visual adjunctive aids, biopsy etc. have been discussed. The traditional treatments include surgery, chemotherapy and radiotherapy. Newer modalities include gene therapy, immunotherapy, etc. have proven to be successful to some extent. Thorough knowledge of the disease and timely diagnosis by the dental professional can prevent metastasis.
Lingen MW, Kalmar JR, Karrison T, Speight PM. Critical evaluation of diagnostic aids for the detection of oral cancer. Oral Oncol 2008; 44(l):10-22.
American Cancer Society. Oral Cancer. Available at: http://www.cancer.org/acs/groups/content@nho/documents/document/oralcancerpdf.pdf. Accessed July 2, 2018.
Oral Cancer Statistics. Oral Cancer in the United States. Available at: http://www.nidcr.nih.gov/FactSheet2.pdf. Accessed July 2, 2018.
The Oral Cancer Foundation web site. Oral Cancer Facts. Available at: http://oralcancerfoundation.org/facts/index/htm. Accessed June 28, 2018.
Kammer C. Shine a light on oral cancer. Dental Products Report. October, 2009. Available at: http://www.dentalprodcutsreport.com/ articles/show/dprl009. Accessed May 3, 2018.
Rethman MP, Carpenter W, Cohen EEW, Epstein J, et al. Evidence based clinical recommendations regarding screening for oral squamous cell carcinomas. J Am Dent Assoc 2010; 141(5):509-20.
Joseph BK, Oral cancer: prevention and detection, Med Princ Pract. 2002; 11(18):32-5.
Kosicki DM, Riva C, Pajarola GF, Burkhardt A, Gratz KW. OralCDx brush biopsy — a tool for early diagnosis of oral squamous cell carcinoma, Schweiz Monatsschr Zahnmed, 2007; 117(3).222-7.
Martin IC, Kerawala CJ, Reed M. The application of toluidine blue as a diagnostic adjunct in the detection of epithelial dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998; 85(4):444-6.
Zhang L, Williams M, Poh CF, et al. Toluidine blue staining identifies high-risk primary oral premalignant lesions with poor outcome. Cancer Res. 2005; 65(17):8017-21.