Polypharmacy: A Prevailing but Neglected Drug Use Issue

  • Sukhdeep Singh
Keywords: Polypharmacy, Drug Interactions, Multimorbidity


With the advancement in medical science, pharmaceutical industry has come up with solutions to countless health related issues. One can easily find treatment for all the ailments, be it prophylactic or curative. Also, with advancement, growth has been seen in the diversity and prevalence of medical problems. People from all age groups are suffering from varying conditions and are taking multiple medications for the same. This phenomenon called polypharmacy has been associated with multimorbidity and is counted as an important risk factor for poor outcomes.


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Author Biography

Sukhdeep Singh

BDS, VPO Jhandi, Tehsil and District Patiala, 147001


Fulton MM & Riley Allen E. Polypharmacy in the elderly: A literature review. Journal of the American Academy of Nurse Practitioners 2005;17:123–32.

https://apps.who.int/iris/bitstream/handle/10665/325454/WHO-UHC-SDS-2019.11-eng.pdf?ua=1. [Last accessed on 19th September, 2019].

Duerden M, Avery T, Payne R. Polypharmacy and medicines optimization: Making it safe and sound. London: The King’s Fund; 2013. Available from https://www.kingsfund.org.uk/sites/default/files/field/field_publication_file/polypharmacy-and-medicines-optimisation-kingsfund-nov13.pdf. [Last accessed on 19 Sep, 2019].

Wise J. Polypharmacy: a necessary evil. BMJ. 2013;347:f7033.

Jokanovic N, Tan EC, Dooley MJ, et al. Prevalence and factors associated with polypharmacy in long-term care facilities: a systematic review. J Am Med Dir Assoc. 2015;16(6):535e1–12.

Narayan S, Nishtala P. Decade‐long temporal trends in the utilization of preventive medicines by centenarians. J Clin Pharm Ther. 2017;42(2):165–9.

Morin L, Vetrano DL, Rizzuto D, et al. Choosing wisely? Measuring the burden of medications in older adults near the end of life: nationwide, longitudinal cohort study. Am J Med. 2017;130(8):927–36.

Williams A, Manias E, Walker R. Interventions to improve medication adherence in people with multiple chronic conditions: a systematic review. J Adv Nurs 2008;63:132–43.

MacLaughlin EJ, Raehl CL, Treadway AK, et al. Assessing medication adherence in the elderly: which tools to use in clinical practice? Drugs Aging 2005;22:231–55.

Halli-Tierney AD, Scarbrough C, Carroll D. Polypharmacy: Evaluating Risks and Deprescribing. Am Fam Physician 2019;100(1):32-8.

Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007;5:345–51.

Baker DW, Wolf MS, Feinglass J, et al. Health literacy and mortality among elderly persons. Arch Intern Med 2007;167:1503–9.

DOI: 10.26440/IHRJ/0307.10300
Published: 2019-10-24
How to Cite
Sukhdeep Singh. Polypharmacy: A Prevailing but Neglected Drug Use Issue. IHRJ [Internet]. 2019Oct.24 [cited 2023Mar.20];3(7):221-3. Available from: https://ihrjournal.com/ihrj/article/view/300