Cardio-Vascular Complications of Hydroxychloroquine Use: Can Impact COVID-19 Pandemic

  • Taruna Singh
  • Rakshit Arora
  • Amrit Sharma
Keywords: Hydroxychloroquine, COVID-19, Coronavirus


As the coronavirus pandemic is on the rise, many compounds with anti-viral properties are under investigation. Hydroxychloroquine (HCQ) being the daily debated daily during this COVID-19 pandemic is an immunomodulatory drug which has been used for indications like malaria, systemic lupus erythematosus and arthritis. Although some researchers have claimed its effectiveness against coronavirus, it results in proarrhythmic effects and drug-induced long QT syndrome. These cardiac issues while using hydroxychloroquine, have limited its use against coronavirus. A literature search was performed, and general safety information of this drug was collected. It can be concluded that this drug leads to cardiovascular events, heart disease, hypotension, tachycardia, and QT interval prolongation, sometimes in combination with other drugs and should be prescribed to the patients only after thoroughly estimating its benefit risk ratio.


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Author Biographies

Taruna Singh

MBBS, M.SC (Forensic Medicine), Private Practitioner and Consultant Doctor, New Delhi, India

Rakshit Arora

MBBS, Private Practitioner, New Delhi

Amrit Sharma

MDS (Oral Pathology), Consultant Dental Surgeon, Shiva Dental Clinic, Gajraula, Uttar Pradesh, India


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DOI: 10.26440/IHRJ/0403.06349
Published: 2020-06-20
How to Cite
Taruna Singh, Rakshit Arora, Amrit Sharma. Cardio-Vascular Complications of Hydroxychloroquine Use: Can Impact COVID-19 Pandemic. IHRJ [Internet]. 2020Jun.20 [cited 2022Aug.11];4(3):56-9. Available from: