Neurological Toxicity Following Treatment with Chemotherapeutic Medicines: A Short Case
Central nervous system toxicity associated with chemotherapeutic agents has been reported in the past. Many potentially promising chemotherapeutic agents are unusable because of central nervous system toxicity. We report a case of neurological complications observed in a subject with a retroperitoneal fibromyxosarcoma treated with Adriamycin and Vincristine. The neurological symptoms started an hour after drug administration and rapidly declined with appropriate therapy.
Gerner RE, Moore GE, Didolker MS. Chemotherapy of disseminated malignant melanoma with dimethyl triazeno imidazole carboxamide and dactinomycin. Cancer 1973;32:756-60.
Gams RA, Carpenter JT. Central nervous system complications after combination treatment with adriamycin (NSC-123127) and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388). Cancer Chemother Rep. 1974 (58):753–4.
Gottlieb JA. Proceedings: Combination chemotherapy for metastatic sarcoma. Cancer Chemother Rep. 1974;58(2):265-70.
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