Ciprofloxacin Associated Renal Issue: A Case Report

Jerry Andrews; Barbara Stewart; Muthu Satyadas

doi:10.26440/IHRJ/0603.06542

Jerry Andrews
Barbara Stewart
Muthu Satyadas

DOI: https://doi.org/10.26440/IHRJ/0603.06542

Keywords: Ciprofloxacin, Renal Insufficiency, Acute Renal Filure, Acute Renal Failure

Abstract

Ciprofloxacin is a very commonly prescribed antibiotic with a wide range of associated adverse events. Cases of renal issues have been reported in literature. We describe a case of an elderly male who suffered from renal insufficiency probably related to ciprofloxacin administered for Pseudomonas infection. Serum therapy was initiated and culprit drug was replaced resulting in satisfactory improvement.

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Author Biographies

Jerry Andrews

MD (Medicine), Consultant physician, Getzville, New York, United States- 14068

Barbara Stewart

MD (Medicine), Consultant physician, Getzville, New York, United States- 14068

Muthu Satyadas

MD (Anesthesiology), Hope Hospital, Jaipur, India

References

Bailey JR, Trott SA, Philbrick JT. Ciprofloxacin-induced acute interstitial nephritis. Am J Nephrol. 1992;12:271–3.

Lo WK, Rolston KV, Rubenstein EB, Bodey GP. Ciprofloxacin-induced nephrotoxicity in patients with cancer. Arch Intern Med. 1993;153:1258–62.

Hottkins R, Fenves AZ, Stephens MK. Acute renal failure secondary to oral ciprofloxacin: A presentation on three cases and a review of the literature. Clin Nephrol. 1989;32:75–8.

Farid S, Mahmood M, Abu Saleh OM, Hamadah A, Nasr SH, Garrigos ZE, et al. Clinical manifestations and outcomes of fluoroquinolone-related acute interstitial nephritis. Mayo Clin Proc. 2018;93:25–31.

Khan M, Ortega LM, Bagwan N, Nayer A. Crystal-induced acute kidney injury due to ciprofloxacin. J Nephropathol. 2015;4:29–31.

Goli R, Mukku KK, Raju SB, Uppin MS. Acute ciprofloxacin-induced crystal nephropathy with granulomatous interstitial nephritis. Indian J Nephrol. 2017;27:231–3.

Kammoun K, Jarraya F, Makni S, Ben Mahmoud L, Kharrat M, Ben Hmida M, et al. Ciprofloxacin-induced crystal nephropathy. Iran J Kidney Dis. 2014;8:240–2.

Yarlagadda SG, Perazella MA. Drug-induced crystal nephropathy: An update. Expert Opin Drug Saf. 2008;7:147–58.

Stratta P, Lazzarich E, Canavese C, Bozzola C, Monga G. Ciprofloxacin crystal nephropathy. Am J Kidney Dis. 2007;50:330–5.

Sedlacek M, Suriawinata AA, Schoolwerth A, Remillard BD. Ciprofloxacin crystal nephropathy—a new cause of acute renal failure. Nephrol Dial Transplant. 2006;21:2339–40.

Liano F, Pascual J, The Madrid Acute Renal Failure Study Group. Epidemiology of acute renal failure: A prospective, multicenter community-based study. Kidney Int. 1996;50:811–8.

Hajji M, Jebali H, Mrad A, Blel Y, Brahmi N, Kheder R, et al. Nephrotoxicity of ciprofloxacin: Five cases and a review of the literature. Drug Saf Case Rep. 2018;5:17.