Primary Gastric Localization of Diffuse Large Cell Lymphoma and Viral Hepatitis C. A Case Report at the Department of Clinical Hematology of University Hospital of Yopougon, Abidjan (Côte d’Ivoire)

  • Packo Dieu-le-Veut Saint-cyr Sylvestre
  • Kouakou Boidy
  • N'dhatz Comoe Emeraude
  • Botti Renee Paule
  • Danho Nanho Clotaire
Keywords: Stomach, Diffuse Large Cell Lymphoma, Hepatitis C Virus

Abstract

Non-Hodgkin's lymphomas are characterized by its clinical and pathological polymorphism. In the stomach, MALT lymphomas are common and mostly associated with Helicobacter Pylori infection. We report a case of 76-year old women with a medical history of chronic stomach pain, addressed for the investigation of normochromic normocytic anemia. The clinical picture included signs of digestive hemorrhage and stomach pain. Gastrointestinal endoscopy and histology noted an unspecified ulcer-budding tumor without signs of Helibacter pylori infection. Immunohistochemistry concluded to diffuse large B cell lymphoma with CD79b +, BCL10 +/-, BCL2+, BCL6 +, MUM1+. The Ann Arbor classification was  stage IE. The serology of Helicobacter pylori was negative. Pre-treatment investigation noted a comorbity with Hepatitis C infection. This study has two interests. Firstly the rarity of the localization of this lymphoma, and secondly, the etiopathological interest because of association with hepatitis C virus.

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Author Biographies

Packo Dieu-le-Veut Saint-cyr Sylvestre

Department of Clinical Hematology, Yopougon Teaching Hospital, P.O. Box 632, Abidjan 21, Cote d’Ivoire

Kouakou Boidy

Department of Clinical Hematology, Yopougon Teaching Hospital, P.O. Box 632, Abidjan 21, Cote d’Ivoire.

N'dhatz Comoe Emeraude

Department of Clinical Hematology, Yopougon Teaching Hospital, P.O. Box 632, Abidjan 21, Cote d’Ivoire.

Botti Renee Paule

Department of Clinical Hematology, Yopougon Teaching Hospital, P.O. Box 632, Abidjan 21, Cote d’Ivoire

Danho Nanho Clotaire

Department of Clinical Hematology, Yopougon Teaching Hospital, P.O. Box 632, Abidjan 21, Cote d’Ivoire.

Published
2019-01-18
How to Cite
Packo Dieu-le-Veut Saint-cyr Sylvestre, Kouakou Boidy, N’dhatz Comoe Emeraude, Botti Renee Paule, & Danho Nanho Clotaire. (2019). Primary Gastric Localization of Diffuse Large Cell Lymphoma and Viral Hepatitis C. A Case Report at the Department of Clinical Hematology of University Hospital of Yopougon, Abidjan (Côte d’Ivoire). International Healthcare Research Journal, 2(10), 243-245. https://doi.org/10.26440/ihrj.v2i10.190

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