The Effect of Nano Bio Fusion Gel as an Adjunct to Conventional Therapy in Gingivitis Patients
INTRODUCTION: Gingival and periodontal diseases are still the most common prevalent oral diseases affecting a community/individual people and can lead to irreversible consequences, both local (bone loss, tooth mobility etc. ) and systemic (Cardiac Disease etc.)
AIM: To compare the efficacy of NBF gingival gel alone and as an adjunct to conventional therapy in patients with gingivitis
MATERIALS AND METHOD: This randomized study design (parallel arm study design) consisted of 7 patients with 21 quadrants and having a score 2 (moderate gingivitis) & 3 (severe gingivitis) based upon the gingival score given by Loe & Silness (1964). All the subjects were evaluated by two parameters i.e. gingival index [Loe & Silness (1964)] and Papillary Bleeding Index [Muhleman (1977)] at baseline and after one month of rendering treatment. Following random allocation (flip of coin), the first Group was given conventional therapy [Scaling and Root Planing(SRP)] followed by NBF gingival gel application, while the 2nd Group was given NBF gel application alone and the 3rd Group was given conventional therapy (SRP) alone. Statistical analysis was done using SPSS version 19.0 using paired t‑test as well as the Wilcoxon Signed Rank test.
RESULTS: After follow up, the highest percentage of mean scores of gingival index decreased among all the groups was seen in group 1 (38.15±5.46), followed by group 3(32.54±7.58) and group 2(18.91±7.62). Similarly, in the Papillary Bleeding Index, the highest percentage reduction was seen in group 1 (82.30±2.39), followed by group 3(53.54±6.02) and group 2(31.71±4.34). All observed values were significant with p≤05.
CONCLUSION: NBF gel seems to provide to boost the immunity of the gingiva and periodontium, and when used as an adjunct to conventional therapy (SRP) can benefit the patient immensely.
Chatterjee A, Sneha V. Evaluate the efficacy of NBF gel as an adjunct to Scaling in gingivitis – a clinical study. Guident 2014:7:86-8.
Beck J, Arbes SJ, Jr. Epidemiology of gingival and periodontal diseases. In: Newman MG, Takei HH, Klokkevold PR, editors. Carranza’s clinical periodontology. St Louis: Saunders/Elsevier; 2006. pp. 110–32.
Flemmig TF. Periodontitis. Ann Periodontol. 1999; 4:32–8.
Cekici A, Kantarci A, Hasturk H, Van Dyke TE. Inflammatory and immune pathways in the pathogenesis of periodontal disease. Periodontol 2000;64(1): 57–80. doi:10.1111/prd.12002.
Salvi GE, Lang NP. The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. Curr Pharm Des. 2005;11(14):1757-69.
Loe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand. 1963;21:533–51.
Mühlemann HR. Psychological and chemical mediators of gingival health. J Prev Dent. 1977;4:6–17.
SPSS Inc. Released 2009. PASW Statistics for Windows, Version 18.0. Chicago: SPSS Inc.
Debnath K, Chatterjee C, Priya VS. Evaluation of Nano-Bio Fusion gel as an adjunct to scaling and root planing in chronic periodontitis: A clinico-microbiological study. J Indian Soc Periodontol. 2016;20(5):543–8. doi: 10.4103/0972-124X.201696
Koo H, Cury JA, Rosalen PL, Ambrosano GM, Ikegaki M, Park YK. Effect of a mouthrinse containing selected propolis on 3-day dental plaque accumulation and polysaccharide formation. Caries Res. 2002;36:445–8.
Coutinho A. Honeybee propolis extract in periodontal treatment: A clinical and microbiological study of propolis in periodontal treatment. Indian J Dent Res. 2012;23:294.