Medically Significant Hypersensitivity Reaction to Dapsone: A Case Report

  • Bharat Sharma
Keywords: Dapsone, Hypersensitivity, Sulfone Syndrome


The drug Dapsone is a component of the World Health Organization multidrug therapy being used against leprosy. Although it has shown a good efficacy during the years, a few subjects develop adverse drug reactions associated with dapsone .We report a case of a patient who was prescribed dapsone as part of multiple drug therapy for leprosy following which he developed Dapsone induced Hypersensitivity Syndrome (DHS). He was prescribed steroids with a tapering dose. His condition worsened after weaning of the oral steroids. He also developed steroid-induced diabetes which was stabilized using anti-diabetic drugs.


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DOI: 10.26440/IHRJ/02_01/157
Published: 2018-04-10
How to Cite
Bharat Sharma. Medically Significant Hypersensitivity Reaction to Dapsone: A Case Report. IHRJ [Internet]. 2018Apr.10 [cited 2024Jun.19];2(1):10-1. Available from: