Denture Stomatitis: Report of a Case with Rarely Used Treatment Modality and Review of Literature
Candida albicans is the most common Candida species isolated from the oral cavity both in healthy and diseased. Candida albicans is a dimorphic fungus existing both in blastopore phase (yeast phase) and the hyphal or mycelial phase. Although these organisms typically colonize mucocutaneous surfaces, the latter can be portals of entry into deeper tissues when host defences are compromised. Denture stomatitis is a common form of oral candidiasis that manifests as a diffuse inflammation of the maxillary denture bearing areas & is associated with angular cheilitis. At least 70% of individuals with clinical signs of denture stomatitis exhibit fungal growth & these conditions most likely result from yeast colonization of the oral mucosa combined with Bacterial colonization. Candida species act as an endogenous infecting agent on tissue predisposed by chronic trauma to microbial invasion. At one time, oral fungal infections were rare findings in general dentist's office. They were more commonly seen in hospitalized and severely debilitated patients. However with enhanced medical and pharmaceutical technology, increasing numbers of ambulatory immunosuppressed individuals with oral fungal infections are seeking out general dentists for diagnosis and treatment of these lesions.
Budtz-Jørgensen E. Oral mucosal lesions associated with the wearing of removable dentures. J Oral Pathol. 1981;10(2):65-80. https://doi.org/10.1111/j.1600-0714.1981.tb01251.x
Moskona D, Kaplan I. Oral lesions in elderly denture wearers. Clinical Preventive Dentistry. 1992;14(5):11-4.
Arendorf TM, Walker DM. Denture stomatitis: a review. J Oral Rehabil. 1987;14(3):217-7. https://doi.org/10.1111/j.1365-2842.1987.tb00713.x
Naik AV, Pai RC. A study of factors contributing to denture stomatitis in a North Indian community. Int J Dent. 2011:589064 https://doi.org/10.1155/2011/589064
Newton AV. Denture sore mouth. Br Dent J. 1962;112:357–9.
Shulman JD, Rivera-Hidalgo F, Beach MM. Risk factors associated with denture stomatitis in the United States. J Oral Pathol Med. 2005;34(6):340-6. https://doi.org/10.1111/j.1600-0714.2005.00287.x
Farah CS, Lynch N, McCullough MJ. Oral fungal infections: an update for the general practitioner. Aust Dent J. 2010;55 (s1):48-54. https://doi.org/10.1111/j.1834-7819.2010.01198.x
Razek MK, Shaaban N. Histochemical and Histopathological Studies of Alveolar Mucosa Under Complete Dentures. J Prosthet Dent. 1978;39:29-39.
Burket LW. Oral Medicine in the Edentulous Patient. In: Burket's Oral Medicine: Diagnosis and Treatment. 7th ed. Philadelphia: Lippincott Publications;1977:568-81.
Arendorf TM, Walker DM. The prevalence and intra-oral distribution of Candida albicans in man. Arch Oral Biol. 1980;25(1):1-10. https://doi.org/10.1016/0003-9969(80)90147-8.
Dorey J, Blasberg B. Oral Mucosal Disorders in Denture Wearers. J Prosthet Dent. 1985;53:210-4.
Scully C, el-Kabir M, Samaranayake LP. Candida and oral candidosis: a review. Crit Rev Oral Biol Med. 1994;5(2):125-157. https://doi.org/10.1177/10454411940050020101
Borba-Santos LP, Reis de Sá LF, Ramos JA, et al. Tacrolimus Increases the Effectiveness of Itraconazole and Fluconazole against Sporothrix spp. Front Microbiol. 2017;8:1759.
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